Details of the Target
General Information of Target
| Target ID | LDTP15483 | |||||
|---|---|---|---|---|---|---|
| Target Name | Inactive phospholipid phosphatase 7 (PLPP7) | |||||
| Gene Name | PLPP7 | |||||
| Gene ID | 84814 | |||||
| Synonyms |
C9orf67; PPAPDC3; Inactive phospholipid phosphatase 7; Phosphatidic acid phosphatase type 2 domain-containing protein 3 |
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| 3D Structure | ||||||
| Sequence |
MAPPPPSPQLLLLAALARLLGPSEVMAGPAEEAGAHCPESLWPLPPQVSPRVTYTRVSPG
QAEDVTFLYHPCAHPWLKLQLALLAYACMANPSLTPDFSLTQDRPLVLTAWGLALEMAWV EPAWAAHWLMRRRRRKQRKKKAWIYCESLSGPAPSEPTPGRGRLCRRGCVQALALAFALR SWRPPGTEVTSQGPRQPSSSGAKRRRLRAALGPQPTRSALRFPSASPGSLKAKQSMAGIP GRESNAPSVPTVSLLPGAPGGNASSRTEAQVPNGQGSPGGCVCSSQASPAPRAAAPPRAA RGPTPRTEEAAWAAMALTFLLVLLTLATLCTRLHRNFRRGESIYWGPTADSQDTVAAVLK RRLLQPSRRVKRSRRRPLLPPTPDSGPEGESSE |
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| Target Bioclass |
Enzyme
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| Family |
PA-phosphatase related phosphoesterase family
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| Subcellular location |
Nucleus envelope
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| Function | Plays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling. Has no detectable enzymatic activity. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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IPM Probe Info |
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C99(1.16) | LDD2230 | [1] | |