Details of the Target
General Information of Target
| Target ID | LDTP15456 | |||||
|---|---|---|---|---|---|---|
| Target Name | Transcription cofactor vestigial-like protein 2 (VGLL2) | |||||
| Gene Name | VGLL2 | |||||
| Gene ID | 245806 | |||||
| Synonyms |
VITO1; Transcription cofactor vestigial-like protein 2; Vgl-2; Protein VITO1 |
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| 3D Structure | ||||||
| Sequence |
MSNLAQFDSDFYQSNFTIDNQEQSGNDSNAYGNLYGSRKQQAGEQPQPASFVPSEMLMSS
GYAGQFFQPASNSDYYSQSPYIDSFDEEPPLLEELGIHFDHIWQKTLTVLNPMKPVDGSI MNETDLTGPILFCVALGATLLLAGKVQFGYVYGMSAIGCLVIHALLNLMSSSGVSYGCVA SVLGYCLLPMVILSGCAMFFSLQGIFGIMSSLVIIGWCSLSASKIFIAALHMEGQQLLVA YPCAILYGLFALLTIF |
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| Target Bioclass |
Other
|
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| Family |
Vestigial family
|
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| Subcellular location |
Nucleus
|
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| Function | May act as a specific coactivator for the mammalian TEFs. May play a role in the development of skeletal muscles. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C117(3.81) | LDD3401 | [1] | |
|
IPM Probe Info |
 |
N.A. | LDD2156 | [2] | |
Competitor(s) Related to This Target
The Interaction Atlas With This Target
References