Details of the Target

General Information of Target

Target ID LDTP15378
Target Name Ral-GDS-related protein (RGL4)
Gene Name RGL4
Gene ID 266747
Synonyms
RGR; Ral-GDS-related protein; hRGR; Ral guanine nucleotide dissociation stimulator-like 4; RalGDS-like 4
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MKLDMTGDCTPVLVLMAAVLTVTGAVPVARLHGALPDARGCHIAQFKSLSPQELQAFKRA
KDALEESLLLKDCRCHSRLFPRTWDLRQLQVRERPMALEAELALTLKVLEATADTDPALV
DVLDQPLHTLHHILSQFRACIQPQPTAGPRTRGRLHHWLYRLQEAPKKESPGCLEASVTF
NLFRLLTRDLNCVASGDLCV
Target Bioclass
Other
Subcellular location
Cytoplasmic vesicle
Uniprot ID
Q8IZJ4
Ensemble ID
ENST00000290691.10
HGNC ID
HGNC:31911

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
ICC108 SNV: p.T370N .
Ishikawa (Heraklio) 02 ER SNV: p.R93G .
JURKAT SNV: p.L100M; p.E189D .
MDST8 SNV: p.G394R .
SNU1 SNV: p.G151W; p.H298Y .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		N.A.  LDD0241  [1]

References

1 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.