Details of the Target
General Information of Target
| Target ID | LDTP15324 | |||||
|---|---|---|---|---|---|---|
| Target Name | Zinc finger protein 354C (ZNF354C) | |||||
| Gene Name | ZNF354C | |||||
| Gene ID | 30832 | |||||
| Synonyms |
KID3; Zinc finger protein 354C; Kidney, ischemia, and developmentally-regulated protein 3; hKID3 |
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| 3D Structure | ||||||
| Sequence |
MGPGERAGGGGDAGKGNAAGGGGGGRSATTAGSRAVSALCLLLSVGSAAACLLLGVQAAA
LQGRVAALEEERELLRRAGPPGALDAWAEPHLERLLREKLDGLAKIRTAREAPSECVCPP GPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGDFGPRGDQGQD GAAGPPGPPGPPGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGEMGPKGPPGPKGEPGVP GKKGDDGTPSQPGPPGPKGEPGSMGPRGENGVDGAPGPKGEPGHRGTDGAAGPRGAPGLK GEQGDTVVIDYDGRILDALKGPPGPQGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKG DPGEPGPAGLKGEAGEMGLSGLPGADGLKGEKGESASDSLQESLAQLIVEPGPPGPPGPP GPMGLQGIQGPKGLDGAKGEKGASGERGPSGLPGPVGPPGLIGLPGTKGEKGRPGEPGLD GFPGPRGEKGDRSERGEKGERGVPGRKGVKGQKGEPGPPGLDQPCPVGPDGLPVPGCWHK |
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| Target Bioclass |
Transcription factor
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| Family |
Krueppel C2H2-type zinc-finger protein family
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| Subcellular location |
Nucleus
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| Function |
Transcriptional repressor that inhibits endothelial angiogenic sprouting. Suppresses osteogenic effects of RUNX2 and may be involved in osteoblastic differentiation. Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal.
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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HHS-465 Probe Info |
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K242(0.00); K245(0.00); Y244(0.00) | LDD2240 | [1] | |