Details of the Target

General Information of Target

Target ID LDTP15313
Target Name Protein FAM131B (FAM131B)
Gene Name FAM131B
Gene ID 9715
Synonyms
KIAA0773; Protein FAM131B
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLLELSEEHKEHLAFLPQVDSAVVAEFGRIAVEFLRRGANPKIYEGAARKLNVSSDTVQH
GVEGLTYLLTESSKLMISELDFQDSVFVLGFSEELNKLLLQLYLDNRKEIRTILSELAPS
LPSYHNLEWRLDVQLASRSLRQQIKPAVTIKLHLNQNGDHNTKVLQTDPATLLHLVQQLE
QALEEMKTNHCRRVVRNIK
Target Bioclass
Other
Family
FAM131 family
Uniprot ID
Q86XD5
Ensemble ID
ENST00000409222.7
HGNC ID
HGNC:22202

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C318(1.64)  LDD3412  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 CCK-81 C318(1.29)  LDD2297  [1]
 LDCM0023  KB03 CCK-81 C318(1.56)  LDD2714  [1]
 LDCM0024  KB05 RT-112 C318(1.64)  LDD3412  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840