Details of the Target

General Information of Target

Target ID LDTP15171
Target Name Cell cycle checkpoint control protein RAD9B (RAD9B)
Gene Name RAD9B
Gene ID 144715
Synonyms
Cell cycle checkpoint control protein RAD9B; DNA repair exonuclease rad9 homolog B; hRAD9B
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLLFLWIETSSEYFNFDWVTFLGTGYWFFWSIFILSLARILTAYSSLLLLLGFLLLWERI
ELYLHLCHKILILLVILLCVILMFIICKFWKERWLVAGLSMQIFAPYVHLVSITVMVILF
WPVAFYVACLEREVRMRRYRMTHSEKKRLKQCNVITRLRGLQVPVGLPFLLILLGLYLMP
LGIYSPCIQEKENLGPKPTIFGHRGAPMLGPENTMMSFEKAVEHGAHGLETDIHLSYDHV
PFLMHDFDLKRTTNIGEVQPESACENPAFFNWDFLSTLNAGKWFVKPELRPFYNMKPLSE
ADKERARNQSIPTLADLLTLAEKERKFVIFDLHRPPPKHPLRHTFVRQVVSVILASKIEQ
HLIFWLPAHDRQYVRSVAPGFQHVGRLVSIETLAKNNISIINVDYKKLFPNGLRDYKAAN
IHINVYTVNEPWLFSLAWCSRINSVTTDNIGLLSQLDHPHFFMTPKFYVFMWLLADIISV
LFIVAIFCFHWRRETEKEKLFETSSTRTDTQSGNLHIAMKPPVRVVEGPWTLAALYPALP
KSGKEHQGHFNFAAPSKKLLPIKNAVTPLKPGKHEIQPPMPTVVFELTQAPTRQATSEAT
FQTTLPTLKVDKPTMPSIEVPYP
Target Bioclass
Enzyme
Family
Rad9 family
Uniprot ID
Q6WBX8
Ensemble ID
ENST00000409246.5
HGNC ID
HGNC:21700

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C96(1.36)  LDD3331  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 MKN-1 C96(1.34)  LDD2497  [1]
 LDCM0023  KB03 MKN-1 C96(1.74)  LDD2914  [1]
 LDCM0024  KB05 MKN-1 C96(1.36)  LDD3331  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840