Details of the Target
General Information of Target
| Target ID | LDTP15133 | |||||
|---|---|---|---|---|---|---|
| Target Name | Dehydrogenase/reductase SDR family member 4-like 2 (DHRS4L2) | |||||
| Gene Name | DHRS4L2 | |||||
| Gene ID | 317749 | |||||
| Synonyms |
SDR25C3; Dehydrogenase/reductase SDR family member 4-like 2; EC 1.1.-.-; Short chain dehydrogenase/reductase family 25C member 3; Protein SDR25C3 |
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| 3D Structure | ||||||
| Sequence |
MAPQRRAATKAPEGNGAAERRNRSSTKKDRAPREVQRLWQRPWLRTAGLGAGFVLTALLL
WSSLGADDGVAEVLARRGEVVAGRFIEVPCSEDYDSHRRFEGCTPRKCGRGVTDVVITRE EAERIRSVAEKGLSLGGSDGGASILDLHSGALSVGKHFVNLYRYFGDKIQNIFSEEDFRL YREVRQKVQLTIAEAFGISASSLHLTKPTFFSRINSTEARTAHDEYWHAHVDKVTYGSFD YTSLLYLSNYLEDFGGGRFMFMEEGANKTVEPRAGRVSFFTSGSENLHRVEKVHWGTRYA ITIAFSCNPDHGIEDPAFP |
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| Target Bioclass |
Enzyme
|
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| Family |
Short-chain dehydrogenases/reductases (SDR) family
|
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| Subcellular location |
Secreted
|
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| Function | Probable oxidoreductase. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
| Cell line | Mutation details | Probe for labeling this protein in this cell | |||
|---|---|---|---|---|---|
| 8505C | Deletion: p.N32RfsTer5 | . | |||
| HT1080 | SNV: p.E94G | DBIA Probe Info | |||
| SW1116 | SNV: p.Q66H | . | |||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C88(1.99) | LDD3319 | [1] | |
|
JW-RF-010 Probe Info |
 |
N.A. | LDD0026 | [2] | |
|
Acrolein Probe Info |
 |
N.A. | LDD0217 | [3] | |
|
NAIA_5 Probe Info |
 |
N.A. | LDD2223 | [4] | |
Competitor(s) Related to This Target
The Interaction Atlas With This Target
References