Details of the Target

General Information of Target

Target ID	LDTP15128
Target Name	Coiled-coil domain-containing protein 174 (CCDC174)
Gene Name	CCDC174
Gene ID	51244
Synonyms	C3orf19; Coiled-coil domain-containing protein 174
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQL DKEGSPEPLDRNNPLEPKNKARFSIPSMTQHHAGRYRCHYYSSAGWSEPSDPLELVMTGF YNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQAL FPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQS LTLQCGSDVGYDRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRCYGAH NLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSRGYFDTFLLTKEG AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPLELMVSG HSGGSSLPPTGPPSTPASHAKDYTVENLIRMGMAGLVLVFLGILLFEAQHSQRNPQDAAG R
Target Bioclass	Other
Subcellular location	Nucleus
Function	Probably involved in neuronal development.
Uniprot ID	Q6PII3
Ensemble ID	ENST00000383794.7
HGNC ID	HGNC:28033

Probe(s) Labeling This Target

ABPP Probe

Click To Hide/Show 1 Probe Related to This Target

Probe name		Structure	Binding Site(Ratio)	Interaction ID	Ref
IA-alkyne Probe Info			C424(3.54)	LDD2157	[1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme

Click To Hide/Show 3 Protein(s) Interacting with This Target

Protein name	Family	Uniprot ID
N-alpha-acetyltransferase 10 (NAA10)	Acetyltransferase family	P41227
Eukaryotic initiation factor 4A-III (EIF4A3)	DEAD box helicase family	P38919
Polyunsaturated fatty acid 5-lipoxygenase (ALOX5)	Lipoxygenase family	P09917

References

1	From chemoproteomic-detected amino acids to genomic coordinates: insights into precise multi-omic data integration. Mol Syst Biol. 2021 Feb;17(2):e9840. doi: 10.15252/msb.20209840. Mass spectrometry data entry: PXD022151