Details of the Target
General Information of Target
| Target ID | LDTP14914 | |||||
|---|---|---|---|---|---|---|
| Target Name | WD repeat-containing protein 72 (WDR72) | |||||
| Gene Name | WDR72 | |||||
| Gene ID | 256764 | |||||
| Synonyms |
WD repeat-containing protein 72 |
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| 3D Structure | ||||||
| Sequence |
MAQPVHSLCSAFGLQCCLLFLLASWGAGATTFQEYQKTGELSTSDHIFPLTPGLVYSIPF
DHIVLHSGQRPPELPKSTEIHEQKRHCNTTRHSKPTDKPTGNSKTIDHKSSTDNHEAPPT SEENSSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTR KSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTT GTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPS PAEPTENRERTANENKKTICTKGKNTPVPEKPTENLGNTTLTTETIKAPVKSTENPEKTA AVTKTIKPSVKVTGDKSLTTTSSHLNKTEVTHQVPTGSFTLITSRTKLSSITSEATGNES HPYLNKDGSQKGIHAGQMGENDSFPAWAIVIVVLVAVILLLVFLGLIFLVSYMMRTRRTL TQNTQYNDAEDEGGPNSYPVYLMEQQNLGMGQIPSPR |
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| Target Bioclass |
Other
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| Subcellular location |
Cytoplasmic vesicle
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| Function |
Plays a major role in formation of tooth enamel. Specifically required during the maturation phase of amelogenesis for normal formation of the enamel matrix and clearance of enamel proteins. May be involved in localization of the calcium transporter SLC24A4 to the ameloblast cell membrane.
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
PAL-AfBPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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STS-1 Probe Info |
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N.A. | LDD0137 | [1] | |