Details of the Target

General Information of Target

Target ID LDTP14905
Target Name Galectin-9B (LGALS9B)
Gene Name LGALS9B
Gene ID 284194
Synonyms
Galectin-9B; Gal-9B; Galectin-9-like protein A
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAAGCSEAPRPAAASDGSLVGQAGVLPCLELPTYAAACALVNSRYSCLVAGPHQRHIALS
PRYLNRKRTGIREQLDAELLRYSESLLGVPIAYDNIKVVGELGDIYDDQGHIHLNIEADF
VIFCPEPGQKLMGIVNKVSSSHIGCLVHGCFNASIPKPEQLSAEQWQTMEINMGDELEFE
VFRLDSDAAGVFCIRGKLNITSLQFKRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEV
DSGTTKLADDADDTPMEESALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSS
GYQSDHKKKKKKRKHSEEAEFTPPLKCSPKRKGKSNFL
Target Bioclass
Other
Function Binds galactosides.
Uniprot ID
Q3B8N2
Ensemble ID
ENST00000324290.5
HGNC ID
HGNC:24842

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C102(0.96)  LDD3310  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 697 C74(2.04); C102(0.89)  LDD2245  [1]
 LDCM0023  KB03 42-MG-BA C102(1.64)  LDD2661  [1]
 LDCM0024  KB05 COLO792 C102(0.96)  LDD3310  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840