Details of the Target

General Information of Target

Target ID LDTP14856
Target Name Pregnancy-specific beta-1-glycoprotein 5 (PSG5)
Gene Name PSG5
Gene ID 5673
Synonyms
Pregnancy-specific beta-1-glycoprotein 5; PS-beta-G-5; PSBG-5; Pregnancy-specific glycoprotein 5; Fetal liver non-specific cross-reactive antigen 3; FL-NCA-3
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MKVWLLLGLLLVHEALEDVTGQHLPKNKRPKEPGENRIKPTNKKVKPKIPKMKDRDSANS
APKTQSIMMQVLDKGRFQKPAATLSLLAGQTVELRCKGSRIGWSYPAYLDTFKDSRLSVK
QNERYGQLTLVNSTSADTGEFSCWVQLCSGYICRKDEAKTGSTYIFFTEKGELFVPSPSY
FDVVYLNPDRQAVVPCRVTVLSAKVTLHREFPAKEIPANGTDIVYDMKRGFVYLQPHSEH
QGVVYCRAEAGGRSQISVKYQLLYVAVPSGPPSTTILASSNKVKSGDDISVLCTVLGEPD
VEVEFTWIFPGQKDERPVTIQDTWRLIHRGLGHTTRISQSVITVEDFETIDAGYYICTAQ
NLQGQTTVATTVEFS
Target Bioclass
Immunoglobulin
Family
Immunoglobulin superfamily, CEA family
Subcellular location
Secreted
Uniprot ID
Q15238
Ensemble ID
ENST00000342951.11
HGNC ID
HGNC:9522

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C262(3.07); C301(3.41)  LDD2284  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 CAL-120 C262(3.07); C301(3.41)  LDD2284  [1]
 LDCM0023  KB03 CAL-120 C262(5.35); C301(4.93)  LDD2701  [1]
 LDCM0024  KB05 CAL-120 C262(7.33); C301(6.07)  LDD3118  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840