Details of the Target
General Information of Target
| Target ID | LDTP14840 | |||||
|---|---|---|---|---|---|---|
| Target Name | Calcipressin-2 (RCAN2) | |||||
| Gene Name | RCAN2 | |||||
| Gene ID | 10231 | |||||
| Synonyms |
DSCR1L1; ZAKI4; Calcipressin-2; Down syndrome candidate region 1-like 1; Myocyte-enriched calcineurin-interacting protein 2; MCIP2; Regulator of calcineurin 2; Thyroid hormone-responsive protein ZAKI-4
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| 3D Structure | ||||||
| Sequence |
MKNEIAAVVFFFTRLVRKHDKLKKEAVERFAEKLTLILQEKYKNHWYPEKPSKGQAYRCI
RVNKFQRVDPDVLKACENSCILYSDLGLPKELTLWVDPCEVCCRYGEKNNAFIVASFENK DENKDEISRKVTRALDKVTSDYHSGSSSSDEETSKEMEVKPSSVTAAASPVYQISELIFP PLPMWHPLPRKKPGMYRGNGHQNHYPPPVPFGYPNQGRKNKPYRPIPVTWVPPPGMHCDR NHWINPHMLAPH |
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| Target Bioclass |
Other
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| Family |
RCAN family
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| Function | Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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DBIA Probe Info |
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C88(1.27) | LDD3404 | [1] | |
Competitor(s) Related to This Target