Details of the Target
General Information of Target
| Target ID | LDTP14614 | |||||
|---|---|---|---|---|---|---|
| Target Name | Thymosin beta-15A (TMSB15A) | |||||
| Gene Name | TMSB15A | |||||
| Gene ID | 11013 | |||||
| Synonyms |
TMSL8; TMSNB; Thymosin beta-15A; NB thymosin beta; Thymosin-like protein 8 |
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| 3D Structure | ||||||
| Sequence |
MGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDG
DFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLG PLIGVQVPKEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALG YELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAMLLRI ARIP |
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| Target Bioclass |
Other
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| Family |
Thymosin beta family
|
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| Subcellular location |
Cytoplasm, cytoskeleton
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| Function | Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C668(1.00) | LDD3332 | [1] | |
Competitor(s) Related to This Target