Details of the Target

General Information of Target

Target ID LDTP14586
Target Name Acylphosphatase-1 (ACYP1)
Gene Name ACYP1
Gene ID 97
Synonyms
ACYPE; Acylphosphatase-1; EC 3.6.1.7; Acylphosphatase, erythrocyte isozyme; Acylphosphatase, organ-common type isozyme; Acylphosphate phosphohydrolase 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MDLLHKNMKHLWFFLLLVAAPRWVLSQVQLQQWGAGLLKPSETLSLTCAVYGGSFSGYYW
SWIRQPPGKGLEWIGEINHSGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYY
CAR
Target Bioclass
Enzyme
Family
Acylphosphatase family
Uniprot ID
P07311
Ensemble ID
ENST00000238618.8
HGNC ID
HGNC:179

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K25(5.78)  LDD0277  [1]
Acrolein
 Probe Info  		N.A.  LDD0221  [2]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0107  IAA HeLa N.A.  LDD0221  [2]
 LDCM0109  NEM HeLa N.A.  LDD0226  [2]

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.