Details of the Target
General Information of Target
| Target ID | LDTP14553 | |||||
|---|---|---|---|---|---|---|
| Target Name | Integrin beta-like protein 1 (ITGBL1) | |||||
| Gene Name | ITGBL1 | |||||
| Gene ID | 9358 | |||||
| Synonyms |
OSCP; TIED; Integrin beta-like protein 1; Osteoblast-specific cysteine-rich protein; Ten integrin EGF-like repeat domain-containing protein |
|||||
| 3D Structure | ||||||
| Sequence |
MVNQSSTPGFLLLGFSEHPGLERTLFVVVLTSYLLTLVGNTLIILLSALDPKLHSPMYFF
LSNLSFLDLCFTTSCVPQMLVNLWGPKKTISFLDCSVQIFIFLSLGTTECILLTVMAFDR YVAVCQPLHYATIIHPRLCWQLASVAWVIGLVESVVQTPSTLHLPFCPDRQVDDFVCEVP ALIRLSCEDTSYNEIQVAVASVFILVVPLSLILVSYGAITWAVLRINSAKGRRKAFGTCS SHLTVVTLFYSSVIAVYLQPKNPYAQERGKFFGLFYAVGTPSLNPLIYTLRNKEVTRAFR RLLGKEMGLTQS |
|||||
| Target Bioclass |
Transporter and channel
|
|||||
| Subcellular location |
Secreted
|
|||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
| Cell line | Mutation details | Probe for labeling this protein in this cell | |||
|---|---|---|---|---|---|
| A431 | SNV: p.F447L | . | |||
| CAL51 | SNV: p.R367L | . | |||
| G401 | SNV: p.D148E | . | |||
| HT29 | SNV: p.A278D | . | |||
| KMCH1 | SNV: p.D456G | DBIA Probe Info | |||
| LOXIMVI | SNV: p.G482E | . | |||
| LS180 | SNV: p.S34R | . | |||
| MDST8 | SNV: p.A60S | . | |||
| MEWO | SNV: p.G120E | . | |||
| SKMEL5 | SNV: p.H265Y | . | |||
| SNU1 | SNV: p.C335G | . | |||
| SUPT1 | SNV: p.D456G | . | |||
| SW948 | SNV: p.D451Y | . | |||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C50(1.84) | LDD3369 | [1] | |
|
IPIAA_H Probe Info |
 |
N.A. | LDD0030 | [2] | |
Competitor(s) Related to This Target
References