General Information of Target

Target ID LDTP14512
Target Name C1q-related factor (C1QL1)
Gene Name C1QL1
Gene ID 10882
Synonyms
C1QRF; CRF; CTRP14; C1q-related factor; C1q and tumor necrosis factor-related protein 14; C1q/TNF-related protein 14; Complement component 1 Q subcomponent-like 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAQFVRNLVEKTPALVNAAVTYSKPRLATFWYYAKVELVPPTPAEIPRAIQSLKKIVNSA
QTGSFKQLTVKEAVLNGLVATEVLMWFYVGEIIGKRGIIGYDV
Target Bioclass
Other
Subcellular location
Secreted
Function May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses.
Uniprot ID
O75973
Ensemble ID
ENST00000253407.4
HGNC ID
HGNC:24182

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C32(4.52)  LDD3487  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 A498 C32(2.55)  LDD2259  [1]
 LDCM0023  KB03 A498 C32(3.39)  LDD2676  [1]
 LDCM0024  KB05 VMRC-RCW C32(4.52)  LDD3487  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840