Details of the Target

General Information of Target

Target ID LDTP14507
Target Name Serpin I2 (SERPINI2)
Gene Name SERPINI2
Gene ID 5276
Synonyms
MEPI; PI14; Serpin I2; Myoepithelium-derived serine protease inhibitor; Pancpin; Pancreas-specific protein TSA2004; Peptidase inhibitor 14; PI-14
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGQEEELLRIAKKLEKMVARKNTEGALDLLKKLHSCQMSIQLLQTTRIGVAVNGVRKHCS
DKEVVSLAKVLIKNWKRLLDSPGPPKGEKGEEREKAKKKEKGLECSDWKPEAGLSPPRKK
REDPKTRRDSVDSKSSASSSPKRPSVERSNSSKSKAESPKTPSSPLTPTFASSMCLLAPC
YLTGDSVRDKCVEMLSAALKADDDYKDYGVNCDKMASEIEDHIYQELKSTDMKYRNRVRS
RISNLKDPRNPGLRRNVLSGAISAGLIAKMTAEEMASDELRELRNAMTQEAIREHQMAKT
GGTTTDLFQCSKCKKKNCTYNQVQTRSADEPMTTFVLCNECGNRWKFC
Target Type
Literature-reported
Target Bioclass
Other
Family
Serpin family
Subcellular location
Secreted
TTD ID
T99351
Uniprot ID
O75830
DrugMap ID
TTFS1T2
Ensemble ID
ENST00000264677.9
HGNC ID
HGNC:8945

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
ONAyne
 Probe Info  		K398(0.80)  LDD0274  [1]

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270