Details of the Target

General Information of Target

Target ID LDTP14497
Target Name P antigen family member 1 (PAGE1)
Gene Name PAGE1
Gene ID 8712
Synonyms
GAGE9; GAGEB1; P antigen family member 1; PAGE-1; AL5; G antigen 9; GAGE-9; G antigen family B member 1; Prostate-associated gene 1 protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPGPPRSLEMGLLTFRDVAIEFSLEEWQHLDIAQQNLYRNVMLENYRNLAFLGIAVSKPD
LITCLEQGKEPWNMKRHEMVDEPPGMCPHFAQDLWPEQGMEDSFQKAILRRYGKYGHENL
QLRKGCKSVDEYKVNKEGYNGLNQCFTTAQSKVFQCDKYLKVFYKFLNSNRPKIRHTEKK
SFKCKKRVKLFCMLSHKTQHKSIYHREKSYKCKECGKTFNWSSTLTNHRKIYTEEKPYKC
EEYNKSPKQLSTLTTHEIIHAGEKLYKCEECGEAFNRSSNLTTHKIIHTGEKPYKCEECG
KAFIWSSTLTEHKKIHTRKKPYKCEECGKAFIWSSTLTRHKRMHTGEKPYKCEECGKAFS
QSSTLTTHKIIHTGEKRYKCLECGKAFKQLSTLTTHKIIHVGEKLYKCEECGKGFNRSSN
LTTHKIIHTGEKPYKCEECGKAFIWSSTLTKHKRIHTREKPYKCEECGKAFIWSSTLTRH
KRMHTGEKPYKCEECGKSFSQSSTLTTHKIIHTGEKPYKCEECGKAFNWSSTLTKHKIIH
TEEKPYKCEKCGKAFKQSSILTNHKRIHTGEKPYKCEECGKSFNRSSTFTKHKVIHTGVK
PYKCEECGKAFFWSSTLTKHKRIHTGEQPYKWEKFGKAFNRSSHLTTDKITHWREILQV
Target Bioclass
Other
Family
GAGE family
Uniprot ID
O75459
Ensemble ID
ENST00000376150.4
HGNC ID
HGNC:4107

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		C115(0.00); C73(0.00)  LDD0147  [1]
TFBX
 Probe Info  		N.A.  LDD0148  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Probable ATP-dependent RNA helicase DDX49 (DDX49) DEAD box helicase family Q9Y6V7
Glutathione S-transferase 3, mitochondrial (MGST3) MAPEG family O14880
Phospholipid phosphatase 4 (PLPP4) PA-phosphatase related phosphoesterase family Q5VZY2
Transporter and channel
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Excitatory amino acid transporter 3 (SLC1A1) Dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family P43005
Solute carrier family 2, facilitated glucose transporter member 5 (SLC2A5) Sugar transporter (TC 2.A.1.1) family P22732
Transferrin receptor protein 1 (TFRC) Peptidase M28 family P02786
Transmembrane protein 14B (TMEM14B) TMEM14 family Q9NUH8
Transmembrane protein 60 (TMEM60) . Q9H2L4
Cytokine and receptor
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
CKLF-like MARVEL transmembrane domain-containing protein 7 (CMTM7) Chemokine-like factor family Q96FZ5
Tumor necrosis factor (TNF) Tumor necrosis factor family P01375
Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Protein FAM9B (FAM9B) FAM9 family Q8IZU0
Transmembrane protein 254 (TMEM254) . Q8TBM7

References

1 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255