Details of the Target
General Information of Target
| Target ID | LDTP14445 | |||||
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| Target Name | Chondroadherin (CHAD) |
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| Gene Name | CHAD | |||||
| Gene ID | 1101 | |||||
| Synonyms |
SLRR4A; Chondroadherin; Cartilage leucine-rich protein |
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| 3D Structure | ||||||
| Sequence |
MTVVGNPRSWSCQWLPILILLLGTGHGPGVEGVTHYKAGDPVILYVNKVGPYHNPQETYH
YYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQLSSAQVEQLR QAIEELYYFEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANVS VRDVKPHSLDGLRPDEFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHWLSII NSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETTSAGSGDDFDQGDNGWKIIHTDVFRF PPYRGLLCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVS SHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWL LVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTVIHMTVGGFLPFSAISV ELYYIFATVWGREQYTLYGILFFVFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVG STGLFIFLYSVFYYARRSNMSGAVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIY VNLKMD |
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| Target Bioclass |
Other
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| Family |
Small leucine-rich proteoglycan (SLRP) family, SLRP class IV subfamily
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| Subcellular location |
Secreted, extracellular space, extracellular matrix
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| Function |
Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important role in the regulation of chondrocyte growth and proliferation.
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
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Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
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DBIA Probe Info |
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C326(1.87) | LDD2268 | [1] | |
Competitor(s) Related to This Target