Details of the Target

General Information of Target

Target ID LDTP14374
Target Name C2 calcium-dependent domain-containing protein 4B (C2CD4B)
Gene Name C2CD4B
Gene ID 388125
Synonyms
FAM148B; NLF2; C2 calcium-dependent domain-containing protein 4B; Nuclear-localized factor 2; Protein FAM148B
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAGRRAQTGSAPPRPAAPHPRPASRAFPQHCRPRDAERPPSPRSPLMPGCELPVGTCPDM
CPAAERAQREREHRLHRLEVVPGCRQDPPRADPQRAVKEYSRPAAGKPRPPPSQLRPPSV
LLATVRYLAGEVAESADIARAEVASFVADRLRAVLLDLALQGAGDAEAAVVLEAALATLL
TVVARLGPDAARGPADPVLLQAQVQEGFGSLRRCYARGAGPHPRQPAFQGLFLLYNLGSV
EALHEVLQLPAALRACPPLRKALAVDAAFREGNAARLFRLLQTLPYLPSCAVQCHVGHAR
REALARFARAFSTPKGQTLPLGFMVNLLALDGLREARDLCQAHGLPLDGEERVVFLRGRY
VEEGLPPASTCKVLVESKLRGRTLEEVVMAEEEDEGTDRPGSPA
Target Bioclass
Other
Family
C2CD4 family
Subcellular location
Nucleus
Function May be involved in inflammatory process. May regulate cell architecture and adhesion.
Uniprot ID
A6NLJ0
Ensemble ID
ENST00000380392.4
HGNC ID
HGNC:33628

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
NAIA_4
 Probe Info  		N.A.  LDD2226  [1]

References

1 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264