Details of the Target

General Information of Target

Target ID LDTP14358
Target Name WAS/WASL-interacting protein family member 3 (WIPF3)
Gene Name WIPF3
Gene ID 644150
Synonyms
CR16; WAS/WASL-interacting protein family member 3; Corticosteroids and regional expression protein 16 homolog
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPRAQLPEDSSAVDMDILFPLDSVIGTELCPSPIPQIIHFVLFVVFSLVILIILRLYIPR
EPSSVPPREEDSENDQAEVGEWLRIGNKYITLKDYRILLKELENLEIYTFLSKKCLKKLS
REGSSHHLPRQVRPGPVYKPAPARNHRPRGGRGKASPTSFHVSPRAPLAPLASMPSSVPK
TSVESLGSPSSLSSSKPREPLCPLKHPSHQPPASTLSPNPTSSTESLGYLSSLSSSQPPE
PLRPLKHPSHKPRGRSLPRRRNPGWVSWSDSMQADSETDTIICPMCKAPERSCPHTWWVP
SSPRVIRGVGRCSDPNLGLSWRQEAARAWCHCTSSQFPFKHPNLPTHLPKASF
Target Bioclass
Other
Family
Verprolin family
Subcellular location
Cytoplasm
Function May be a regulator of cytoskeletal organization. May have a role in spermatogenesis.
Uniprot ID
A6NGB9
Ensemble ID
ENST00000242140.10
HGNC ID
HGNC:22004

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C221(0.81)  LDD1508  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0215  AC10 HEK-293T C221(0.81)  LDD1508  [1]
 LDCM0277  AC18 HEK-293T C221(1.04)  LDD1516  [1]
 LDCM0279  AC2 HEK-293T C221(0.91)  LDD1518  [1]
 LDCM0286  AC26 HEK-293T C221(0.95)  LDD1525  [1]
 LDCM0295  AC34 HEK-293T C221(1.05)  LDD1534  [1]
 LDCM0304  AC42 HEK-293T C221(0.93)  LDD1543  [1]
 LDCM0313  AC50 HEK-293T C221(0.95)  LDD1552  [1]
 LDCM0321  AC58 HEK-293T C221(0.90)  LDD1560  [1]
 LDCM0405  CL18 HEK-293T C221(1.04)  LDD1609  [1]
 LDCM0419  CL30 HEK-293T C221(1.05)  LDD1623  [1]
 LDCM0432  CL42 HEK-293T C221(1.04)  LDD1636  [1]
 LDCM0445  CL54 HEK-293T C221(0.79)  LDD1648  [1]
 LDCM0451  CL6 HEK-293T C221(1.03)  LDD1654  [1]
 LDCM0458  CL66 HEK-293T C221(1.01)  LDD1661  [1]
 LDCM0471  CL78 HEK-293T C221(1.02)  LDD1674  [1]
 LDCM0485  CL90 HEK-293T C221(0.84)  LDD1688  [1]

References

1 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402