Details of the Target

General Information of Target

Target ID LDTP13844
Target Name VPS9 domain-containing protein 1 (VPS9D1)
Gene Name VPS9D1
Gene ID 9605
Synonyms
ATPBL; C16orf7; VPS9 domain-containing protein 1; Protein ATP-BL
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSPSAKKRPKNSRVSKMQDEKLRDETEQPVSKVIERNRLRTVLKNLSLLKLLKSSNRRIQ
ELHKLAKRCWHSLLSVPKILRISSGENSACNKTKQNNEEFQEIGCSEKELKSKKLESTGD
PKKKEYKEWKSQVQSGMRNKEKTSLAAMPRKEKHIEPEVPRTSRDDSLNPGVQGRQPLTE
GPRVIFIKPYRNRTPMGHMKQLDVADQWIWFEGLPTRIHLPAPRVMCRSSTLRWVKRRCT
RFCSASLEMPMWHPYKVDVTWTRARGASRGWRSRHQLKGRNGWRNSRVYK
Target Bioclass
Other
Uniprot ID
Q9Y2B5
Ensemble ID
ENST00000389386.8
HGNC ID
HGNC:13526

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CCK81 SNV: p.E551D .
ICC137 SNV: p.L288V .
Ishikawa (Heraklio) 02 ER SNV: p.G312D .
JURKAT SNV: p.A302T .
LNCaP clone FGC SNV: p.Q400Ter .
MCC13 SNV: p.G583D .
MELHO SNV: p.D171N .
MELJUSO SNV: p.L423V .
NCIH2172 Deletion: p.Y480TfsTer53 .
SKNSH SNV: p.P548H .
VCAP SNV: p.P252T .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
NAIA_5
 Probe Info  		N.A.  LDD2225  [1]

References

1 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264