Details of the Target
General Information of Target
| Target ID | LDTP13654 | |||||
|---|---|---|---|---|---|---|
| Target Name | Rab effector Noc2 (RPH3AL) | |||||
| Gene Name | RPH3AL | |||||
| Gene ID | 9501 | |||||
| Synonyms |
NOC2; Rab effector Noc2; No C2 domains protein; Rabphilin-3A-like protein |
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| 3D Structure | ||||||
| Sequence |
MAHVGDCTQTPWLPVLVVSLMCSARAEYSNCGENEYYNQTTGLCQECPPCGPGEEPYLSC
GYGTKDEDYGCVPCPAEKFSKGGYQICRRHKDCEGFFRATVLTPGDMENDAECGPCLPGY YMLENRPRNIYGMVCYSCLLAPPNTKECVGATSGASANFPGTSGSSTLSPFQHAHKELSG QGHLATALIIAMSTIFIMAIAIVLIIMFYILKTKPSAPACCTSHPGKSVEAQVSKDEEKK EAPDNVVMFSEKDEFEKLTATPAKPTKSENDASSENEQLLSRSVDSDEEPAPDKQGSPEL CLLSLVHLAREKSATSNKSAGIQSRRKKILDVYANVCGVVEGLSPTELPFDCLEKTSRML SSTYNSEKAVVKTWRHLAESFGLKRDEIGGMTDGMQLFDRISTAGYSIPELLTKLVQIER LDAVESLCADILEWAGVVPPASQPHAAS |
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| Target Bioclass |
Other
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| Subcellular location |
Cytoplasm
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| Function | Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells. Acts as a potential RAB3B effector protein in epithelial cells. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C123(1.61) | LDD3420 | [1] | |
Competitor(s) Related to This Target