Details of the Target
General Information of Target
| Target ID | LDTP13588 | |||||
|---|---|---|---|---|---|---|
| Target Name | Protein-arginine deiminase type-3 (PADI3) | |||||
| Gene Name | PADI3 | |||||
| Gene ID | 51702 | |||||
| Synonyms |
PAD3; PDI3; Protein-arginine deiminase type-3; EC 3.5.3.15; Peptidylarginine deiminase III; Protein-arginine deiminase type III |
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| 3D Structure | ||||||
| Sequence |
MAESENRKELSESSQEEAGNQIMVEGLGEHLERGEDAAAGLGDDGKCGEEAAAGLGEEGE
NGEDTAAGSGEDGKKGGDTDEDSEADRPKGLIGYVLDTDFVESLPVKVKYRVLALKKLQT RAANLESKFLREFHDIERKFAEMYQPLLEKRRQIINAIYEPTEEECEYKSDSEDCDDEEM CHEEMYGNEEGMVHEYVDEDDGYEDYYYDYAVEEEEEEEEEDDIEATGEENKEEEDPKGI PDFWLTVLKNVDTLTPLIKKYDEPILKLLTDIKVKLSDPGEPLSFTLEFHFKPNEYFKNE LLTKTYVLKSKLAYYDPHPYRGTAIEYSTGCEIDWNEGKNVTLKTIKKKQKHRIWGTIRT VTEDFPKDSFFNFFSPHGITSNGRDGNDDFLLGHNLRTYIIPRSVLFFSGDALESQQEGV VREVNDAIYDKIIYDNWMAAIEEVKACCKNLEALVEDIDR |
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| Target Type |
Literature-reported
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| Target Bioclass |
Enzyme
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| Family |
Protein arginine deiminase family
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| Subcellular location |
Cytoplasm
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| Function | Catalyzes the deimination of arginine residues of proteins. | |||||
| TTD ID | ||||||
| Uniprot ID | ||||||
| DrugMap ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
| ChEMBL ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C564(1.53); C547(2.86) | LDD3312 | [1] | |
Competitor(s) Related to This Target