Details of the Target
General Information of Target
| Target ID | LDTP13534 | |||||
|---|---|---|---|---|---|---|
| Target Name | Protein-arginine deiminase type-1 (PADI1) | |||||
| Gene Name | PADI1 | |||||
| Gene ID | 29943 | |||||
| Synonyms |
PAD1; PDI1; Protein-arginine deiminase type-1; EC 3.5.3.15; Peptidylarginine deiminase I; Protein-arginine deiminase type I |
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| 3D Structure | ||||||
| Sequence |
MLFIFNFLFSPLPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVS
QKNNDLTSCCFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGS CLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADI AMVICDTPQKALVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLG KEHFRKPVPPSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDV AISYLPLAHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYD KVQNEAKTPLKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGA APMSTSVMTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVA DMNYFTVNNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDR KKNIFKLAQGEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKL GVKGSFEELCQNQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLK AKRGELSKYFRTQIDSLYEHIQD |
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| Target Bioclass |
Enzyme
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| Family |
Protein arginine deiminase family
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| Subcellular location |
Cytoplasm
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| Function | Catalyzes the deimination of arginine residues of proteins. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
| ChEMBL ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C339(0.62); C233(0.97) | LDD3364 | [1] | |
Competitor(s) Related to This Target