Details of the Target
General Information of Target
| Target ID | LDTP12998 | |||||
|---|---|---|---|---|---|---|
| Target Name | Disks large-associated protein 2 (DLGAP2) | |||||
| Gene Name | DLGAP2 | |||||
| Synonyms |
C8orf68; DAP2; ERICH1-AS1; Disks large-associated protein 2; DAP-2; PSD-95/SAP90-binding protein 2; SAP90/PSD-95-associated protein 2; SAPAP2 |
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| 3D Structure | ||||||
| Sequence |
MASFRKLTLSEKVPPNHPSRKKVNFLDMSLDDIIIYKELEGTNAEEEKNKRQNHSKKESP
SRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCSDN YEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSDRSQGQL KRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSERSHGHSKRSRSQGDLVD TQSDLIATQRDLIATQKDLIATQRDLIATQRDLIVTQRDLVATERDLINQSGRSHGQSER HQRYSTGKNTITT |
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| Target Bioclass |
Other
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| Family |
SAPAP family
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| Subcellular location |
Cell membrane
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| Function |
May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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DBIA Probe Info |
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C96(3.08) | LDD3398 | [1] | |
Competitor(s) Related to This Target