Details of the Target

General Information of Target

Target ID LDTP12995
Target Name Neurotrimin (NTM)
Gene Name NTM
Gene ID 50863
Synonyms
IGLON2; NT; Neurotrimin; hNT; IgLON family member 2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MKIFKCYFKHTLQQKVFILFLTLWLLSLLKLLNVRRLFPQKDIYLVEYSLSTSPFVRNRY
THVKDEVRYEVNCSGIYEQEPLEIGKSLEIRRRDIIDLEDDDVVAMTSDCDIYQTLRGYA
QKLVSKEEKSFPIAYSLVVHKDAIMVERLIHAIYNQHNIYCIHYDRKAPDTFKVAMNNLA
KCFSNIFIASKLEAVEYAHISRLQADLNCLSDLLKSSIQWKYVINLCGQDFPLKSNFELV
SELKKLNGANMLETVKPPNSKLERFTYHHELRRVPYEYVKLPIRTNISKEAPPHNIQIFV
GSAYFVLSQAFVKYIFNNSIVQDFFAWSKDTYSPDEHFWATLIRVPGIPGEISRSAQDVS
DLQSKTRLVKWNYYEGFFYPSCTGSHLRSVCIYGAAELRWLIKDGHWFANKFDSKVDPIL
IKCLAEKLEEQQRDWITLPSEKLFMDRNLTTTS
Target Bioclass
Immunoglobulin
Family
Immunoglobulin superfamily, IgLON family
Subcellular location
Cell membrane
Function Neural cell adhesion molecule.
Uniprot ID
Q9P121
Ensemble ID
ENST00000374784.5
HGNC ID
HGNC:17941

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C83(1.13)  LDD2397  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 IGR-39 C83(1.13)  LDD2397  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840