Details of the Target

General Information of Target

Target ID LDTP12967
Target Name Zinc finger protein with KRAB and SCAN domains 7 (ZKSCAN7)
Gene Name ZKSCAN7
Gene ID 55888
Synonyms
ZNF167; ZNF448; ZNF64; Zinc finger protein with KRAB and SCAN domains 7; Zinc finger protein 167; Zinc finger protein 448; Zinc finger protein 64
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MASASGAMAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYC
VRPNSGIIDPGSTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDE
LMDSKLRCVFEMPNENDKLNDMEPSKAVPLNASKQDGPMPKPHSVSLNDTETRKLMEECK
RLQGEMMKLSEENRHLRDEGLRLRKVAHSDKPGSTSTASFRDNVTSPLPSLLVVIAAIFI
GFFLGKFIL
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q9P0L1
Ensemble ID
ENST00000273320.7
HGNC ID
HGNC:12955

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
AGS SNV: p.L181P .
CHL1 SNV: p.P170L .
GB1 SNV: p.P48H .
MFE319 Deletion: p.E436KfsTer183 .
NCIH23 SNV: p.T574I .
SKMM2 SNV: p.H513P .
SNU869 SNV: p.S194I .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
HHS-465
 Probe Info  		K577(0.00); K580(0.00); K689(0.00); K692(0.00)  LDD2240  [1]

References

1 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010