Details of the Target
General Information of Target
| Target ID | LDTP12801 | |||||
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| Target Name | Probable polypeptide N-acetylgalactosaminyltransferase 8 (GALNT8) | |||||
| Gene Name | GALNT8 | |||||
| Gene ID | 26290 | |||||
| Synonyms |
Probable polypeptide N-acetylgalactosaminyltransferase 8; EC 2.4.1.41; Polypeptide GalNAc transferase 8; GalNAc-T8; pp-GaNTase 8; Protein-UDP acetylgalactosaminyltransferase 8; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 8
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| 3D Structure | ||||||
| Sequence |
MDVERLQEALKDFEKRGKKEVCPVLDQFLCHVAKTGETMIQWSQFKGYFIFKLEKVMDDF
RTSAPEPRGPPNPNVEYIPFDEMKERILKIVTGFNGIPFTIQRLCELLTDPRRNYTGTDK FLRGVEKNVMVVSCVYPSSEKNNSNSLNRMNGVMFPGNSPSYTERSNINGPGTPRPLNRP KVSLSAPMTTNGLPESTDSKEANLQQNEEKNHSDSSTSESEVSSVSPLKNKHPDEDAVEA EGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEASSSSQDKDKDSRCTRQHCTEED EEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLH SEGSENEGPVSSSSSDCRETEELVGSNSSKTGEILSESSMENDDEATEVTDEPMEQD |
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| Target Bioclass |
Enzyme
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| Family |
Glycosyltransferase 2 family, GalNAc-T subfamily
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| Subcellular location |
Golgi apparatus membrane
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| Function | Probably catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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DBIA Probe Info |
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C395(2.00) | LDD3380 | [1] | |
Competitor(s) Related to This Target