Details of the Target

General Information of Target

Target ID	LDTP12530
Target Name	Tryptase gamma (TPSG1)
Gene Name	TPSG1
Gene ID	25823
Synonyms	PRSS31; TMT; Tryptase gamma; EC 3.4.21.-; Serine protease 31; Transmembrane tryptase) [Cleaved into: Tryptase gamma light chain; Tryptase gamma heavy chain]
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MRQLKGKPKKETSKDKKERKQAMQEARQQITTVVLPTLAVVVLLIVVFVYVATRPTITE
Target Bioclass	Enzyme
Family	Peptidase S1 family, Tryptase subfamily
Subcellular location	Membrane
Uniprot ID	Q9NRR2
Ensemble ID	ENST00000234798.5
HGNC ID	HGNC:14134
ChEMBL ID	CHEMBL4955

Probe(s) Labeling This Target

ABPP Probe

Click To Hide/Show 1 Probe Related to This Target

Probe name		Structure	Binding Site(Ratio)	Interaction ID	Ref
IA-alkyne Probe Info			N.A.	LDD0165	[1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other

Click To Hide/Show 2 Protein(s) Interacting with This Target

Protein name				Family	Uniprot ID
Hippocalcin-like protein 1 (HPCAL1)				Recoverin family	P37235
Neurocalcin-delta (NCALD)				Recoverin family	P61601

References

1	SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18. Mass spectrometry data entry*: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060