Details of the Target
General Information of Target
| Target ID | LDTP12496 | |||||
|---|---|---|---|---|---|---|
| Target Name | Spectrin beta chain, non-erythrocytic 5 (SPTBN5) | |||||
| Gene Name | SPTBN5 | |||||
| Gene ID | 51332 | |||||
| Synonyms |
BSPECV; HUBSPECV; HUSPECV; Spectrin beta chain, non-erythrocytic 5; Beta-V spectrin |
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| 3D Structure | ||||||
| Sequence |
MAEAATGFLEQLKSCIVWSWTYLWTVWFFIVLFLVYILRVPLKINDNLSTVSMFLNTLTP
KFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSVSHLRPLLGGVDNNSSNNSNSSN GDSDSNRQSVSECKVWRNPLNLFRGAEYNRYTWVTGREPLTYYDMNLSAQDHQTFFTCDS DHLRPADAIMQKAWRERNPQARISAAHEALEINEIRSRVEVPLIASSTIWEIKLLPKCAT AYILLAEEEATTIAEAEKLFKQALKAGDGCYRRSQQLQHHGSQYEAQHRRDTNVLVYIKR RLAMCARRLGRTREAVKMMRDLMKEFPLLSMFNIHENLLEALLELQAYADVQAVLAKYDD ISLPKSATICYTAALLKARAVSDKFSPEAASRRGLSTAEMNAVEAIHRAVEFNPHVPKYL LEMKSLILPPEHILKRGDSEAIAYAFFHLAHWKRVEGALNLLHCTWEGTFRMIPYPLEKG HLFYPYPICTETADRELLPSFHEVSVYPKKELPFFILFTAGLCSFTAMLALLTHQFPELM GVFAKAMIDIFCSAEFRDWNCKSIFMRVEDELEIPPAPQSQHFQN |
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| Target Bioclass |
Other
|
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| Family |
Spectrin family
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| Subcellular location |
Cytoplasm, cytoskeleton
|
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C2657(1.96) | LDD2324 | [1] | |
|
IA-alkyne Probe Info |
 |
C70(1.08) | LDD2182 | [2] | |
Competitor(s) Related to This Target
| Competitor ID | Name | Cell line | Binding Site(Ratio) | Interaction ID | Ref |
|---|---|---|---|---|---|
| LDCM0573 | Fragment11 | Ramos | C70(0.64) | LDD2190 | [2] |
| LDCM0576 | Fragment14 | Ramos | C70(1.68) | LDD2193 | [2] |
| LDCM0566 | Fragment4 | Ramos | C70(2.11) | LDD2184 | [2] |
| LDCM0569 | Fragment7 | Ramos | C70(5.46) | LDD2186 | [2] |
| LDCM0022 | KB02 | Ramos | C70(1.08) | LDD2182 | [2] |
| LDCM0023 | KB03 | Ramos | C70(0.84) | LDD2183 | [2] |
| LDCM0024 | KB05 | Ramos | C70(0.86) | LDD2185 | [2] |
References