Details of the Target
General Information of Target
| Target ID | LDTP12264 | |||||
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| Target Name | Polypeptide N-acetylgalactosaminyltransferase 9 (GALNT9) | |||||
| Gene Name | GALNT9 | |||||
| Gene ID | 50614 | |||||
| Synonyms |
Polypeptide N-acetylgalactosaminyltransferase 9; EC 2.4.1.41; Polypeptide GalNAc transferase 9; GalNAc-T9; pp-GaNTase 9; Protein-UDP acetylgalactosaminyltransferase 9; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9
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| 3D Structure | ||||||
| Sequence |
MGIKTALPAAELGLYSLVLSGALAYAGRGLLEASQDGAHRKAFRESVRPGWEYIGRKMDV
ADFEWVMWFTSFRNVIIFALSGHVLFAKLCTMVAPKLRSWMYAVYGALAVMGTMGPWYLL LLLGHCVGLYVASLLGQPWLCLGLGLASLASFKMDPLISWQSGFVTGTFDLQEVLFHGGS SFTVLRCTSFALESCAHPDRHYSLADLLKYNFYLPFFFFGPIMTFDRFHAQVSQVEPVRR EGELWHIRAQAGLSVVAIMAVDIFFHFFYILTIPSDLKFANRLPDSALAGLAYSNLVYDW VKAAVLFGVVNTVACLDHLDPPQPPKCITALYVFAETHFDRGINDWLCKYVYNHIGGEHS AVIPELAATVATFAITTLWLGPCDIVYLWSFLNCFGLNFELWMQKLAEWGPLARIEASLS VQMSRRVRALFGAMNFWAIIMYNLVSLNSLKFTELVARRLLLTGFPQTTLSILFVTYCGV QLVKERERTLALEEEQKQDKEKPE |
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| Target Bioclass |
Enzyme
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| Family |
Glycosyltransferase 2 family, GalNAc-T subfamily
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| Subcellular location |
Golgi apparatus membrane
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| Function |
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Does not glycosylate apomucin or SDC3.
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
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Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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DBIA Probe Info |
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C525(1.72) | LDD3468 | [1] | |
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YN-1 Probe Info |
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N.A. | LDD0447 | [2] | |
Competitor(s) Related to This Target
References