Details of the Target

General Information of Target

Target ID LDTP12249
Target Name Zinc finger and BTB domain-containing protein 26 (ZBTB26)
Gene Name ZBTB26
Gene ID 57684
Synonyms
KIAA1572; ZNF481; Zinc finger and BTB domain-containing protein 26; Zinc finger protein 481; Zinc finger protein Bioref
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRAQTCPSVCSCSNQFSKV
ICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAF
NGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLG
ELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQ
GLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHH
NPWNCNCDILWLSWWIKDMAPSNTACCARCNTPPNLKGRYIGELDQNYFTCYAPVIVEPP
ADLNVTEGMAAELKCRASTSLTSVSWITPNGTVMTHGAYKVRIAVLSDGTLNFTNVTVQD
TGMYTCMVSNSVGNTTASATLNVTAATTTPFSYFSTVTVETMEPSQDEARTTDNNVGPTP
VVDWETTNVTTSLTPQSTRSTEKTFTIPVTDINSGIPGIDEVMKTTKIIIGCFVAITLMA
AVMLVIFYKMRKQHHRQNHHAPTRTVEIINVDDEITGDTPMESHLPMPAIEHEHLNHYNS
YKSPFNHTTTVNTINSIHSSVHEPLLIRMNSKDNVQETQI
Target Bioclass
Transcription factor
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q9HCK0
Ensemble ID
ENST00000373654.1
HGNC ID
HGNC:23383

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
Acrolein
 Probe Info  		N.A.  LDD0224  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0109  NEM HeLa N.A.  LDD0224  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 8 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Peroxisomal bifunctional enzyme (EHHADH) Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase family Q08426
Cell division cycle 7-related protein kinase (CDC7) Ser/Thr protein kinase family O00311
Helicase ARIP4 (RAD54L2) SNF2/RAD54 helicase family Q9Y4B4
TNF receptor-associated factor 4 (TRAF4) TNF receptor-associated factor family Q9BUZ4
E3 ubiquitin-protein ligase TRIM41 (TRIM41) TRIM/RBCC family Q8WV44
SUMO-conjugating enzyme UBC9 (UBE2I) Ubiquitin-conjugating enzyme family P63279
E3 ubiquitin-protein ligase LNX (LNX1) . Q8TBB1
E3 ubiquitin-protein ligase RNF4 (RNF4) . P78317
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Hsp90 co-chaperone Cdc37 (CDC37) CDC37 family Q16543
Transcription factor
Click To Hide/Show 8 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Telomere zinc finger-associated protein (ZBTB48) Krueppel C2H2-type zinc-finger protein family P10074
Homeobox-containing protein 1 (HMBOX1) . Q6NT76
Zinc finger and BTB domain-containing protein 12 (ZBTB12) . Q9Y330
Zinc finger and BTB domain-containing protein 26 (ZBTB26) . Q9HCK0
Zinc finger and BTB domain-containing protein 34 (ZBTB34) . Q8NCN2
Zinc finger and BTB domain-containing protein 6 (ZBTB6) . Q15916
Zinc finger and BTB domain-containing protein 9 (ZBTB9) . Q96C00
Zinc finger protein 408 (ZNF408) . Q9H9D4
Other
Click To Hide/Show 13 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Testis-specific gene 10 protein (TSGA10) CEP135/TSGA10 family Q9BZW7
Death domain-associated protein 6 (DAXX) DAXX family Q9UER7
Dynein regulatory complex subunit 4 (GAS8) DRC4 family O95995
Segment polarity protein dishevelled homolog DVL-3 (DVL3) DSH family Q92997
PDZ domain-containing protein GIPC2 (GIPC2) GIPC family Q8TF65
Periplakin (PPL) Plakin or cytolinker family O60437
UV excision repair protein RAD23 homolog A (RAD23A) RAD23 family P54725
Small ubiquitin-related modifier 1 (SUMO1) Ubiquitin family P63165
Small ubiquitin-related modifier 5 (SUMO1P1) Ubiquitin family G2XKQ0
Axin-1 (AXIN1) . O15169
Caspase recruitment domain-containing protein 10 (CARD10) . Q9BWT7
Lethal(3)malignant brain tumor-like protein 2 (L3MBTL2) . Q969R5
Mortality factor 4-like protein 2 (MORF4L2) . Q15014

References

1 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.