Details of the Target

General Information of Target

Target ID LDTP11385
Target Name Complement C1q tumor necrosis factor-related protein 2 (C1QTNF2)
Gene Name C1QTNF2
Gene ID 114898
Synonyms
CTRP2; Complement C1q tumor necrosis factor-related protein 2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MLWRQLIYWQLLALFFLPFCLCQDEYMESPQTGGLPPDCSKCCHGDYSFRGYQGPPGPPG
PPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYPGIPPELQIAF
MASLATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYV
YLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRMGNGALHGDHQRFSTFAGF
LLFETK
Target Bioclass
Other
Subcellular location
Secreted
Function Involved in the regulation of lipid metabolism in adipose tissue and liver.
Uniprot ID
Q9BXJ5
Ensemble ID
ENST00000652664.2
HGNC ID
HGNC:14325

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C9(1.74)  LDD3424  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 Hep 3B2.1-7 C9(1.20)  LDD2353  [1]
 LDCM0023  KB03 Hep 3B2.1-7 C9(0.88)  LDD2770  [1]
 LDCM0024  KB05 SK-HEP1 C9(1.74)  LDD3424  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840