Details of the Target
General Information of Target
| Target ID | LDTP11378 | |||||
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| Target Name | Cytosolic 5'-nucleotidase 1A (NT5C1A) |
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| Gene Name | NT5C1A | |||||
| Gene ID | 84618 | |||||
| Synonyms |
Cytosolic 5'-nucleotidase 1A; cN1A; EC 3.1.3.5; EC 3.1.3.89; EC 3.1.3.99; 5'-deoxynucleotidase; Cytosolic 5'-nucleotidase IA; cN-I; cN-IA |
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| 3D Structure | ||||||
| Sequence |
MKSGPGIQAAIDLTAGAAGGTACVLTGQPFDTIKVKMQTFPDLYKGLTDCFLKTYAQVGL
RGFYKGTGPALMAYVAENSVLFMCYGFCQQFVRKVAGMDKQAKLSDLQTAAAGSFASAFA ALALCPTELVKCRLQTMYEMEMSGKIAKSHNTIWSVVKGILKKDGPLGFYHGLSSTLLQE VPGYFFFFGGYELSRSFFASGRSKDELGPVHLMLSGGVAGICLWLVVFPVDCIKSRIQVL SMYGKQAGFIGTLLSVVRNEGIVALYSGLKATMIRAIPANGALFVAYEYSRKMMMKQLEA Y |
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| Target Bioclass |
Enzyme
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| Family |
5'-nucleotidase type 3 family
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| Subcellular location |
Cytoplasm
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| Function |
Catalyzes the hydrolysis of ribonucleotide and deoxyribonucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside. AMP is the major substrate but can also hydrolyze dCMP and IMP.
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
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IPM Probe Info |
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C273(1.33) | LDD2229 | [1] | |