Details of the Target
General Information of Target
| Target ID | LDTP11337 | |||||
|---|---|---|---|---|---|---|
| Target Name | Cell division cycle-associated protein 7 (CDCA7) | |||||
| Gene Name | CDCA7 | |||||
| Gene ID | 83879 | |||||
| Synonyms |
JPO1; Cell division cycle-associated protein 7; Protein JPO1 |
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| 3D Structure | ||||||
| Sequence |
MRTLFNLLWLALACSPVHTTLSKSDAKKAASKTLLEKSQFSDKPVQDRGLVVTDLKAESV
VLEHRSYCSAKARDRHFAGDVLGYVTPWNSHGYDVTKVFGSKFTQISPVWLQLKRRGREM FEVTGLHDVDQGWMRAVRKHAKGLHIVPRLLFEDWTYDDFRNVLDSEDEIEELSKTVVQV AKNQHFDGFVVEVWNQLLSQKRVGLIHMLTHLAEALHQARLLALLVIPPAITPGTDQLGM FTHKEFEQLAPVLDGFSLMTYDYSTAHQPGPNAPLSWVRACVQVLDPKSKWRSKILLGLN FYGMDYATSKDAREPVVGARYIQTLKDHRPRMVWDSQASEHFFEYKKSRSGRHVVFYPTL KSLQVRLELARELGVGVSIWELGQGLDYFYDLL |
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| Target Bioclass |
Other
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| Subcellular location |
Nucleus
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| Function |
Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator.
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
IPM Probe Info |
 |
N.A. | LDD0241 | [1] | |
|
DBIA Probe Info |
 |
C418(3.76) | LDD3352 | [2] | |
|
Acrolein Probe Info |
 |
N.A. | LDD0226 | [3] | |
|
4-Iodoacetamidophenylacetylene Probe Info |
 |
N.A. | LDD0038 | [4] | |
|
IA-alkyne Probe Info |
 |
N.A. | LDD0036 | [4] | |
|
Lodoacetamide azide Probe Info |
 |
N.A. | LDD0037 | [4] | |
Competitor(s) Related to This Target
The Interaction Atlas With This Target
References