Details of the Target
General Information of Target
| Target ID | LDTP10672 | |||||
|---|---|---|---|---|---|---|
| Target Name | N-acetylmuramoyl-L-alanine amidase (PGLYRP2) | |||||
| Gene Name | PGLYRP2 | |||||
| Gene ID | 114770 | |||||
| Synonyms |
PGLYRPL; PGRPL; N-acetylmuramoyl-L-alanine amidase; EC 3.5.1.28; Peptidoglycan recognition protein 2; Peptidoglycan recognition protein long; PGRP-L |
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| 3D Structure | ||||||
| Sequence |
MTVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIG
IINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNS VPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ |
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| Target Bioclass |
Enzyme
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| Family |
N-acetylmuramoyl-L-alanine amidase 2 family
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| Subcellular location |
Secreted
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| Function | May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C506(3.85); C196(1.81) | LDD2268 | [1] | |
Competitor(s) Related to This Target