Details of the Target
General Information of Target
| Target ID | LDTP10665 | |||||
|---|---|---|---|---|---|---|
| Target Name | N-acetylneuraminate 9-O-acetyltransferase (CASD1) | |||||
| Gene Name | CASD1 | |||||
| Gene ID | 64921 | |||||
| Synonyms |
C7orf12; N-acetylneuraminate 9-O-acetyltransferase; EC 2.3.1.45; CAS1 domain-containing protein 1; Sialate O-acetyltransferase; SOAT |
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| 3D Structure | ||||||
| Sequence |
MACAGLLTVCLLRPPAPQPQPQTPRHPQLAPDPGPAGHTLFQDVFRRADKNDDGKLSFEE
FQNYFADGVLSLGELQELFSGIDGHLTDNLETEKLCDYFSEHLGVYRPVLAALESLNRAV LAAMDATKLEYERASKVDQFVTRFLLRETVSQLQALQSSLEGASDTLEAQAHGWRSDAES VEAQSRLCGSRRAGRRALRSVSRSSTWSPGSSDTGRSSEAEMQWRLQVNRLQELIDQLEC KVRAVGPGPHKGGPSWYPPEPGPCWRPGPHSVPSQAPRLEPLREEDLAKGPDLHILMAQR QVQVAEEGLQDFHRALRCYVDFTGAQSHCLHVSAQKMLDGASFTLYEFWQDEASWRRHQQ SPGSKAFQRILIDHLRAPDTLTTVFFPASWWIMNNN |
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| Target Bioclass |
Enzyme
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| Family |
PC-esterase family, CASD1 subfamily
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| Subcellular location |
Golgi apparatus membrane
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| Function |
O-acetyltransferase that catalyzes 9-O-acetylation of sialic acids. Sialic acids are sugars at the reducing end of glycoproteins and glycolipids, and are involved in various processes such as cell-cell interactions, host-pathogen recognition.
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
IPM Probe Info |
 |
N.A. | LDD0241 | [1] | |
|
DBIA Probe Info |
 |
C344(2.32) | LDD2268 | [2] | |
Competitor(s) Related to This Target
References