Details of the Target

General Information of Target

Target ID LDTP10631
Target Name TOX high mobility group box family member 2 (TOX2)
Gene Name TOX2
Gene ID 84969
Synonyms
C20orf100; GCX1; TOX high mobility group box family member 2; Granulosa cell HMG box protein 1; GCX-1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAEDLDELLDEVESKFCTPDLLRRGMVEQPKGCGGGTHSSDRNQAKAKETLRSTETFKKE
DDLDSLINEILEEPNLDKKPSKLKSKSSGNTSVRASIEGLGKSCSPVYLGGSSIPCGIGT
NISWRACDHLRCIACDFLVVSYDDYMWDKSCDYLFFRNNMPEFHKLKAKLIKKKGTRAYA
CQCSWRTIEEVTDLQTDHQLRWVCGKH
Target Bioclass
Transcription factor
Subcellular location
Nucleus
Function Putative transcriptional activator involved in the hypothalamo-pituitary-gonadal system.
Uniprot ID
Q96NM4
Ensemble ID
ENST00000341197.9
HGNC ID
HGNC:16095

Probe(s) Labeling This Target

PAL-AfBPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STS-1
 Probe Info  		N.A.  LDD0136  [1]
STS-2
 Probe Info  		N.A.  LDD0138  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Maspardin (SPG21) AB hydrolase superfamily Q9NZD8
Prolyl 4-hydroxylase subunit alpha-3 (P4HA3) P4HA family Q7Z4N8
Transcription factor
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Heat shock transcription factor, Y-linked (HSFY1; HSFY2) HSF family Q96LI6
PHD finger protein 1 (PHF1) Polycomblike family O43189
T-cell leukemia homeobox protein 3 (TLX3) . O43711
Other
Click To Hide/Show 12 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Acyl carrier protein, mitochondrial (NDUFAB1) Acyl carrier protein (ACP) family O14561
Centromere protein P (CENPP) CENP-P/CTF19 family Q6IPU0
Homer protein homolog 3 (HOMER3) Homer family Q9NSC5
RIB43A-like with coiled-coils protein 1 (RIBC1) RIB43A family Q8N443
Tektin-4 (TEKT4) Tektin family Q8WW24
Tektin-5 (TEKT5) Tektin family Q96M29
Transcription elongation factor A protein 2 (TCEA2) TFS-II family Q15560
UNC5C-like protein (UNC5CL) Unc-5 family Q8IV45
Cleavage stimulation factor subunit 2 tau variant (CSTF2T) . Q9H0L4
Enkurin domain-containing protein 1 (ENKD1) . Q9H0I2
Galectin-4 (LGALS4) . P56470
Heat shock factor 2-binding protein (HSF2BP) . O75031

References

1 Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling. Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8551-6. doi: 10.1002/anie.201300683. Epub 2013 Jun 10.