Details of the Target

General Information of Target

Target ID LDTP10376
Target Name Zinc finger protein 764 (ZNF764)
Gene Name ZNF764
Gene ID 92595
Synonyms
Zinc finger protein 764
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPGCPCPGCGMAGPRLLFLTALALELLERAGGSQPALRSRGTATACRLDNKESESWGALL
SGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSFALGGLLGN
VFLHLLPEAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALEKMFLDSKEEGTSQA
PNKDPTAAAAALNGGHCLAQPAAEPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASF
LVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICT
QSPKGVVGCSPAAEETAAWVLPFTSGGFLYIALVNVLPDLLEEEDPWRSLQQLLLLCAGI
VVMVLFSLFVD
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function
Zinc finger protein that functions as a cofactor for steroid hormone receptors, such as NR3C1/GR. Directs NR3C1/GR transcriptional activity toward specific biologic pathways by changing NR3C1/GR binding and transcriptional activity on the glucocorticoid-responsive genes.
Uniprot ID
Q96H86
Ensemble ID
ENST00000252797.6
HGNC ID
HGNC:28200

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		N.A.  LDD0167  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Probable E3 ubiquitin-protein ligase DTX2 (DTX2) Deltex family Q86UW9
Ubiquitin thioesterase ZRANB1 (ZRANB1) Peptidase C64 family Q9UGI0
Dual specificity protein kinase CLK2 (CLK2) CMGC Ser/Thr protein kinase family P49760
E3 ubiquitin-protein ligase TRIM38 (TRIM38) . O00635
Transporter and channel
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Importin subunit alpha-4 (KPNA3) Importin alpha family O00505
MyoD family inhibitor (MDFI) MDFI family Q99750
Transcription factor
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Zinc finger protein 837 (ZNF837) Krueppel C2H2-type zinc-finger protein family Q96EG3
Zinc finger protein 408 (ZNF408) . Q9H9D4
Other
Click To Hide/Show 18 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cysteine-rich tail protein 1 (CYSRT1) CYSRT1 family A8MQ03
Segment polarity protein dishevelled homolog DVL-3 (DVL3) DSH family Q92997
Golgin subfamily A member 6-like protein 9 (GOLGA6L9) GOLGA6 family A6NEM1
Protein Hook homolog 1 (HOOK1) Hook family Q9UJC3
Keratin-associated protein 1-3 (KRTAP1-3) KRTAP type 1 family Q8IUG1
Keratin-associated protein 10-7 (KRTAP10-7) KRTAP type 10 family P60409
Keratin-associated protein 10-9 (KRTAP10-9) KRTAP type 10 family P60411
Keratin-associated protein 12-2 (KRTAP12-2) KRTAP type 12 family P59991
Keratin-associated protein 2-4 (KRTAP2-4) KRTAP type 2 family Q9BYR9
Keratin-associated protein 4-4 (KRTAP4-4) KRTAP type 4 family Q9BYR3
Zinc finger protein 330 (ZNF330) NOA36 family Q9Y3S2
Protein phosphatase 1 regulatory subunit 37 (PPP1R37) PPP1R37 family O75864
Suppressor of fused homolog (SUFU) SUFU family Q9UMX1
Armadillo repeat-containing protein 7 (ARMC7) . Q9H6L4
Coiled-coil domain-containing protein 125 (CCDC125) . Q86Z20
Four and a half LIM domains protein 5 (FHL5) . Q5TD97
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) . P52597
PRKCA-binding protein (PICK1) . Q9NRD5

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060