Details of the Target
General Information of Target
| Target ID | LDTP10236 | |||||
|---|---|---|---|---|---|---|
| Target Name | Receptor-transporting protein 4 (RTP4) | |||||
| Gene Name | RTP4 | |||||
| Gene ID | 64108 | |||||
| Synonyms |
IFRG28; Z3CXXC4; Receptor-transporting protein 4; 28 kDa interferon-responsive protein; 3CxxC-type zinc finger protein 4 |
|||||
| 3D Structure | ||||||
| Sequence |
MASGVGAAFEELPHDGTCDECEPDEAPGAEEVCRECGFCYCRRHAEAHRQKFLSHHLAEY
VHGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDE SDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCP DHGLDLSTYCQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIELVER LKFKSSDPKVTRDQMKMFIQQEFKKVQKVIADEEQKALHLVDIQEAMATAHVTEILADIQ SHMDRLMTQMAQAKEQLDTSNESAEPKAEGDEEGPSGASEEEDT |
|||||
| Target Bioclass |
Other
|
|||||
| Family |
TMEM7 family
|
|||||
| Subcellular location |
Membrane
|
|||||
| Function |
Probable chaperone protein which facilitates trafficking and functional cell surface expression of some G-protein coupled receptors (GPCRs). Promotes functional expression of the bitter taste receptor TAS2R16. Also promotes functional expression of the opioid receptor heterodimer OPRD1-OPRM1.
|
|||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C37(1.26) | LDD2337 | [1] | |
Competitor(s) Related to This Target