Details of the Target
General Information of Target
| Target ID | LDTP10160 | |||||
|---|---|---|---|---|---|---|
| Target Name | Serine/threonine-protein kinase ULK4 (ULK4) | |||||
| Gene Name | ULK4 | |||||
| Gene ID | 54986 | |||||
| Synonyms |
Serine/threonine-protein kinase ULK4; EC 2.7.11.1; Unc-51-like kinase 4 |
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| 3D Structure | ||||||
| Sequence |
MSVGFIGAGQLAYALARGFTAAGILSAHKIIASSPEMNLPTVSALRKMGVNLTRSNKETV
KHSDVLFLAVKPHIIPFILDEIGADVQARHIVVSCAAGVTISSVEKKLMAFQPAPKVIRC MTNTPVVVQEGATVYATGTHALVEDGQLLEQLMSSVGFCTEVEEDLIDAVTGLSGSGPAY AFMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATIH ALHFLESGGFRSLLINAVEASCIRTRELQSMADQEKISPAALKKTLLDRVKLESPTVSTL TPSSPGKLLTRSLALGGKKD |
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| Target Bioclass |
Enzyme
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| Family |
Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily
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| Function | May be involved in the remodeling of cytoskeletal components, such as alpha-tubulin, and in this way regulates neurite branching and elongation, as well as cell motility. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
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DBIA Probe Info |
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C141(4.14) | LDD2268 | [1] | |
Competitor(s) Related to This Target