Details of the Target
General Information of Target
| Target ID | LDTP09866 | |||||
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| Target Name | Cyclin-dependent kinase-like 2 (CDKL2) |
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| Gene Name | CDKL2 | |||||
| Gene ID | 8999 | |||||
| Synonyms |
Cyclin-dependent kinase-like 2; EC 2.7.11.22; Protein kinase p56 KKIAMRE; Serine/threonine-protein kinase KKIAMRE |
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| 3D Structure | ||||||
| Sequence |
MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKA
TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH GDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQ IFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLG GGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYM EKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEE FSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGT KSEQLSNP |
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| Target Type |
Literature-reported
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| Target Bioclass |
Enzyme
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| Family |
Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily
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| Subcellular location |
Cytoplasm
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| TTD ID | ||||||
| Uniprot ID | ||||||
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| Ensemble ID | ||||||
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| ChEMBL ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
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DBIA Probe Info |
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C816(3.33) | LDD3310 | [1] | |
Competitor(s) Related to This Target