Details of the Target

General Information of Target

Target ID LDTP09730
Target Name Transmembrane protein 234 (TMEM234)
Gene Name TMEM234
Gene ID 56063
Synonyms
C1orf91; Transmembrane protein 234
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAASLGQVLALVLVAALWGGTQPLLKRASAGLQRVHEPTWAQQLLQEMKTLFLNTEYLMP
FLLNQCGSLLYYLTLASTDLTLAVPICNSLAIIFTLIVGKALGEDIGGKRAVAGMVLTVI
GISLCITSSVPWTAELQLHGKGQLQTLSQKCKREASGTQSERFG
Target Bioclass
Transporter and channel
Family
TMEM234 family
Subcellular location
Membrane
Uniprot ID
Q8WY98
Ensemble ID
ENST00000309777.11
HGNC ID
HGNC:28837

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C122(6.33)  LDD3367  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 NUGC-3 C122(4.78)  LDD2533  [1]
 LDCM0023  KB03 NUGC-3 C122(6.97)  LDD2950  [1]
 LDCM0024  KB05 NUGC-3 C122(6.33)  LDD3367  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840