Details of the Target
General Information of Target
| Target ID | LDTP09617 | |||||
|---|---|---|---|---|---|---|
| Target Name | Ubiquitin-conjugating enzyme E2 Q2 (UBE2Q2) | |||||
| Gene Name | UBE2Q2 | |||||
| Gene ID | 92912 | |||||
| Synonyms |
Ubiquitin-conjugating enzyme E2 Q2; EC 2.3.2.23; E2 ubiquitin-conjugating enzyme Q2; Ubiquitin carrier protein Q2; Ubiquitin-protein ligase Q2 |
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| 3D Structure | ||||||
| Sequence |
MSVSGLKAELKFLASIFDKNHERFRIVSWKLDELHCQFLVPQQGSPHSLPPPLTLHCNIT
ESYPSSSPIWFVDSEDPNLTSVLERLEDTKNNNLLRQQLKWLICELCSLYNLPKHLDVEM LDQPLPTGQNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENL AILEKIRKTQRQDHLNGAVSGSVQASDRLMKELRDIYRSQSYKTGIYSVELINDSLYDWH VKLQKVDPDSPLHSDLQILKEKEGIEYILLNFSFKDNFPFDPPFVRVVLPVLSGGYVLGG GALCMELLTKQGWSSAYSIESVIMQINATLVKGKARVQFGANKNQYNLARAQQSYNSIVQ IHEKNGWYTPPKEDG |
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| Target Bioclass |
Enzyme
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| Family |
Ubiquitin-conjugating enzyme family
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| Subcellular location |
Cytoplasm
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| Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
AOyne Probe Info |
 |
15.00 | LDD0443 | [1] | |
The Interaction Atlas With This Target
The Protein(s) Related To This Target
Transporter and channel
| Protein name | Family | Uniprot ID | |||
|---|---|---|---|---|---|
| Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (GNB2) | WD repeat G protein beta family | P62879 | |||
Other
| Protein name | Family | Uniprot ID | |||
|---|---|---|---|---|---|
| Heat shock protein beta-1 (HSPB1) | Small heat shock protein (HSP20) family | P04792 | |||