Details of the Target
General Information of Target
| Target ID | LDTP09443 | |||||
|---|---|---|---|---|---|---|
| Target Name | Potassium voltage-gated channel subfamily V member 2 (KCNV2) | |||||
| Gene Name | KCNV2 | |||||
| Gene ID | 169522 | |||||
| Synonyms |
Potassium voltage-gated channel subfamily V member 2; Voltage-gated potassium channel subunit Kv8.2 |
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| 3D Structure | ||||||
| Sequence |
MLKQSERRRSWSYRPWNTTENEGSQHRRSICSLGARSGSQASIHGWTEGNYNYYIEEDED
GEEEDQWKDDLAEEDQQAGEVTTAKPEGPSDPPALLSTLNVNVGGHSYQLDYCELAGFPK TRLGRLATSTSRSRQLSLCDDYEEQTDEYFFDRDPAVFQLVYNFYLSGVLLVLDGLCPRR FLEELGYWGVRLKYTPRCCRICFEERRDELSERLKIQHELRAQAQVEEAEELFRDMRFYG PQRRRLWNLMEKPFSSVAAKAIGVASSTFVLVSVVALALNTVEEMQQHSGQGEGGPDLRP ILEHVEMLCMGFFTLEYLLRLASTPDLRRFARSALNLVDLVAILPLYLQLLLECFTGEGH QRGQTVGSVGKVGQVLRVMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLLLFIAM GIFTFSAAVYSVEHDVPSTNFTTIPHSWWWAAVSISTVGYGDMYPETHLGRFFAFLCIAF GIILNGMPISILYNKFSDYYSKLKAYEYTTIRRERGEVNFMQRARKKIAECLLGSNPQLT PRQEN |
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| Target Bioclass |
Transporter and channel
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| Family |
Potassium channel family, V (TC 1.A.1.2) subfamily, Kv8.2/KCNV2 sub-subfamily
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| Subcellular location |
Cell membrane
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| Function | Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
| ChEMBL ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
IA-alkyne Probe Info |
 |
C202(20.00) | LDD0315 | [1] | |
Competitor(s) Related to This Target