General Information of Target

Target ID LDTP09167
Target Name Steroid receptor-associated and regulated protein (SRARP)
Gene Name SRARP
Gene ID 149563
Synonyms
C1orf64; ERRF; SSPR; Steroid receptor-associated and regulated protein; Estrogen receptor-related factor; ER-related factor; Steroid receptor-regulated protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAPSEDPRDWRANLKGTIRETGLETSSGGKLAGHQKTVPTAHLTFVIDCTHGKQLSLAAT
ASPPQAPSPNRGLVTPPMKTYIVFCGENWPHLTRVTPMGGGCLAQARATLPLCRGSVASA
SFPVSPLCPQEVPEAKGKPVKAAPVRSSTWGTVKDSLKALSSCVCGQAD
Target Bioclass
Other
Function May regulate the transcriptional function of androgen and estrogen receptors.
Uniprot ID
Q8NEQ6
Ensemble ID
ENST00000329454.2
HGNC ID
HGNC:28339

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info 
C102(3.58)  LDD2268  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0022  KB02 BRX211 C102(3.58)  LDD2268  [1]
 LDCM0023  KB03 BRX211 C102(6.09)  LDD2685  [1]
 LDCM0024  KB05 BRX250 C102(1.39)  LDD3103  [1]

References

1 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840