Details of the Target

General Information of Target

Target ID LDTP08970
Target Name Melanoma-associated antigen B6 (MAGEB6)
Gene Name MAGEB6
Gene ID 158809
Synonyms
Melanoma-associated antigen B6; Cancer/testis antigen 3.4; CT3.4; MAGE-B6 antigen
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPRGHKSKLRTCEKRQETNGQPQGLTGPQATAEKQEESHSSSSSSRACLGDCRRSSDASI
PQESQGVSPTGSPDAVVSYSKSDVAANGQDEKSPSTSRDASVPQESQGASPTGSPDAGVS
GSKYDVAANGQDEKSPSTSHDVSVPQESQGASPTGSPDAGVSGSKYDVAAEGEDEESVSA
SQKAIIFKRLSKDAVKKKACTLAQFLQKKFEKKESILKADMLKCVRREYKPYFPQILNRT
SQHLVVAFGVELKEMDSSGESYTLVSKLGLPSEGILSGDNALPKSGLLMSLLVVIFMNGN
CATEEEVWEFLGLLGIYDGILHSIYGDARKIITEDLVQDKYVVYRQVCNSDPPCYEFLWG
PRAYAETTKMRVLRVLADSSNTSPGLYPHLYEDALIDEVERALRLRA
Target Bioclass
Other
Uniprot ID
Q8N7X4
Ensemble ID
ENST00000379034.1
HGNC ID
HGNC:23796

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C200(1.04)  LDD1511  [1]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0281  AC21 HEK-293T C200(1.00)  LDD1520  [1]
 LDCM0289  AC29 HEK-293T C200(0.97)  LDD1528  [1]
 LDCM0298  AC37 HEK-293T C200(1.04)  LDD1537  [1]
 LDCM0307  AC45 HEK-293T C200(1.07)  LDD1546  [1]
 LDCM0312  AC5 HEK-293T C200(1.09)  LDD1551  [1]
 LDCM0316  AC53 HEK-293T C200(1.12)  LDD1555  [1]
 LDCM0325  AC61 HEK-293T C200(1.01)  LDD1564  [1]
 LDCM0248  AKOS034007472 HEK-293T C200(1.04)  LDD1511  [1]
 LDCM0409  CL21 HEK-293T C200(1.51)  LDD1613  [1]
 LDCM0422  CL33 HEK-293T C200(0.93)  LDD1626  [1]
 LDCM0435  CL45 HEK-293T C200(1.01)  LDD1639  [1]
 LDCM0448  CL57 HEK-293T C200(1.16)  LDD1651  [1]
 LDCM0461  CL69 HEK-293T C200(1.26)  LDD1664  [1]
 LDCM0475  CL81 HEK-293T C200(0.95)  LDD1678  [1]
 LDCM0484  CL9 HEK-293T C200(1.06)  LDD1687  [1]
 LDCM0488  CL93 HEK-293T C200(1.12)  LDD1691  [1]

References

1 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402