Details of the Target

General Information of Target

Target ID LDTP08961
Target Name PACRG-like protein (PACRGL)
Gene Name PACRGL
Gene ID 133015
Synonyms
C4orf28; PACRG-like protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MQKSEGSGGTQLKNRATGNYDQRTSSSTQLKHRNAVQGSKSSLSTSSPESARKLHPRPSD
KLNPKTINPFGEQSRVPSAFAAIYSKGGIPCRLVHGSVKHRLQWECPPESLSFDPLLITL
AEGLRETKHPYTFVSKEGFRELLLVKGAPEKAIPLLPRLIPVLKAALVHSDDEVFERGLN
ALVQLSVVVGPSLNDHLKHLLTSLSKRLMDKKFKEPITSALQKLEQHGGSGSLSIIKSKI
PTYCSICC
Target Bioclass
Other
Uniprot ID
Q8N7B6
Ensemble ID
ENST00000295290.12
HGNC ID
HGNC:28442

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
DU145 SNV: p.S27N .
SNU1 SNV: p.A166T .
SUIT2 SNV: p.Y131S .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IA-alkyne
 Probe Info  		N.A.  LDD0162  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Tyrosine--tRNA ligase, cytoplasmic (YARS1) Class-I aminoacyl-tRNA synthetase family P54577
NADH dehydrogenase flavoprotein 2, mitochondrial (NDUFV2) Complex I 24 kDa subunit family P19404
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Junctophilin-3 (JPH3) Junctophilin family Q8WXH2
Transcription factor
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
ALX homeobox protein 1 (ALX1) Paired homeobox family Q15699
Myogenic factor 5 (MYF5) . P13349
Myogenin (MYOG) . P15173
Other
Click To Hide/Show 7 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Protein BEX5 (BEX5) BEX family Q5H9J7
Reticulocalbin-3 (RCN3) CREC family Q96D15
Golgin subfamily A member 2 (GOLGA2) GOLGA2 family Q08379
Protein TASOR 2 (TASOR2) TASOR family Q5VWN6
General transcription factor 3C polypeptide 3 (GTF3C3) . Q9Y5Q9
Putative uncharacterized protein TXNRD3NB (TXNRD3NB) . Q6F5E7
Sprouty-related, EVH1 domain-containing protein 1 (SPRED1) . Q7Z699

References

1 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060