Details of the Target
General Information of Target
| Target ID | LDTP08884 | |||||
|---|---|---|---|---|---|---|
| Target Name | Zinc finger protein 276 (ZNF276) | |||||
| Gene Name | ZNF276 | |||||
| Gene ID | 92822 | |||||
| Synonyms |
CENP-Z; ZFP276; ZNF477; Zinc finger protein 276; Zfp-276; Zinc finger protein 477 |
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| 3D Structure | ||||||
| Sequence |
MKRDRLGRFLSPGSSRQCGASDGGGGVSRTRGRPSLSGGPRVDGATARRAWGPVGSCGDA
GEDGADEAGAGRALAMGHCRLCHGKFSSRSLRSISERAPGASMERPSAEERVLVRDFQRL LGVAVRQDPTLSPFVCKSCHAQFYQCHSLLKSFLQRVNASPAGRRKPCAKVGAQPPTGAE EGACLVDLITSSPQCLHGLVGWVHGHAASCGALPHLQRTLSSEYCGVIQVVWGCDQGHDY TMDTSSSCKAFLLDSALAVKWPWDKETAPRLPQHRGWNPGDAPQTSQGRGTGTPVGAETK TLPSTDVAQPPSDSDAVGPRSGFPPQPSLPLCRAPGQLGEKQLPSSTSDDRVKDEFSDLS EGDVLSEDENDKKQNAQSSDESFEPYPERKVSGKKSESKEAKKSEEPRIRKKPGPKPGWK KKLRCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDR YLQRHVKLIHTEVRNYICDECGQTFKQRKHLLVHQMRHSGAKPLQCEVCGFQCRQRASLK YHMTKHKAETELDFACDQCGRRFEKAHNLNVHMSMVHPLTQTQDKALPLEAEPPPGPPSP SVTTEGQAVKPEPT |
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| Target Bioclass |
Transcription factor
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| Subcellular location |
Nucleus
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| Function | May be involved in transcriptional regulation. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
| Cell line | Mutation details | Probe for labeling this protein in this cell | |||
|---|---|---|---|---|---|
| HUCCT1 | SNV: p.G19W | DBIA Probe Info | |||
| IM95 | Deletion: p.R320GfsTer33 | . | |||
| Ishikawa (Heraklio) 02 ER | SNV: p.H274Q | . | |||
| MFE319 | SNV: p.G58E; p.G292R | . | |||
| MINO | SNV: p.E62Ter | . | |||
| MOLT4 | SNV: p.H197Y | . | |||
| TKKK | SNV: p.G288R | DBIA Probe Info | |||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
DBIA Probe Info |
 |
C436(1.06); C441(1.06) | LDD0078 | [1] | |
Competitor(s) Related to This Target
References